Tesamorelin

Tesamorelin is a synthetic growth hormone-releasing hormone (GHRH) analogue that stimulates the pituitary gland to secrete endogenous growth hormone (GH). It is commonly used in research for fat metabolism, muscle recovery, and supporting tissue repair.

$80.00

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For laboratory research use only. Not for human or animal use or consumption. Not a drug, food, dietary supplement, or cosmetic. Not approved by the FDA for any medical use.

Description

Tesamorelin is a 44–amino acid synthetic peptide that mimics naturally occurring growth hormone-releasing hormone (GHRH). It acts on the pituitary gland to increase the pulsatile secretion of growth hormone (GH), which in turn raises IGF-1 levels, enhances lipolysis, reduces visceral fat, and supports tissue repair and metabolic health.

Mechanism of Action

  • Pituitary Stimulation: Promotes endogenous GH release in a physiologic, pulsatile pattern

  • IGF-1 Elevation: Enhances muscle repair, cellular growth, and metabolic regulation

  • Fat Metabolism: Reduces visceral adipose tissue and supports body composition improvement

  • Restoration of Physiologic GH Pulses: Unlike direct GH therapy, it maintains hormonal balance naturally

Dosage Guidelines (Research Use)

  • Morning (AM): 1–2 mg subcutaneous injection before workout in a fasted state, 5 days/week

  • Evening (PM): 1–2 mg subcutaneous injection at night to align with natural GH release

  • Cycle Length: 8–10 weeks with a recommended off-cycle of 4–8 weeks

  • Higher Dosage: Should be split into two daily administrations

Important Notes

  • Carbs and fat may blunt GH release; take at least 30 minutes before eating or 2 hours after

  • Generally well tolerated; potential mild side effects include injection site redness, headache, dizziness, or flushing

  • Caution advised in individuals with active malignancy or pituitary disorders

Useful Information

  • Class: Growth Hormone–Releasing Hormone (GHRH) analogue

  • Research Focus: Metabolic health, tissue repair, visceral fat reduction, and GH modulation

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