Ipamorelin is a synthetic growth hormone secretagogue that stimulates endogenous GH release by selectively activating the ghrelin receptor. Commonly used in research for muscle recovery, fat metabolism, and tissue repair, it offers clean GH pulses without significantly affecting cortisol or prolactin.
$45.00
For laboratory research use only. Not for human or animal use or consumption. Not a drug, food, dietary supplement, or cosmetic. Not approved by the FDA for any medical use.
Ipamorelin (Aib-His-D-2-Nal-D-Phe-Lys-NH₂) is a synthetic pentapeptide that functions as a selective growth hormone secretagogue. It binds to the ghrelin (GHSR-1a) receptor in the pituitary gland, stimulating the release of endogenous growth hormone (GH) in a physiological, pulsatile manner. Unlike other GH secretagogues, Ipamorelin does not significantly elevate cortisol or prolactin levels, providing a “cleaner” GH pulse for research purposes.
Selectively binds to ghrelin receptors in the pituitary
Stimulates endogenous GH release without affecting cortisol or prolactin
Enhances muscle recovery, fat metabolism, and tissue repair
Aligns with the body’s natural GH cycle when administered at night, optimizing GH secretion during deep sleep
Typical Dose: 300 mcg – 1 mg per administration
Frequency:
Morning, fasted, before workouts (5 days per week)
Evening, 30–60 minutes before sleep, to match natural GH cycles
Cycle Length: 8–10 weeks, followed by an off-cycle of 4–8 weeks
Higher doses may be split into two administrations per day
Carbohydrates and fats may blunt GH release; best taken 30 minutes before meals or 2 hours after eating
Generally well tolerated
Occasional redness, swelling, or mild discomfort at the injection site
Rare effects: headache, transient dizziness, or flushing
Class: Selective growth hormone secretagogue (GHRP analog)
Category: Growth Hormone Peptides
Primary Research Focus: GH release, muscle recovery, fat metabolism, tissue repair
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