Description
IGF-1 LR3 (Long Arg3 Insulin-like Growth Factor-1) is a recombinant peptide analogue of human IGF-1 designed for enhanced stability, extended half-life, and increased bioavailability. Modifications including arginine substitution at position 3 and removal of the N-terminal glutamic acid reduce binding to IGF-binding proteins (IGFBPs), allowing a half-life of 20–30 hours compared to 20–30 minutes for native IGF-1.
Mechanism of Action
-
Acts downstream of Growth Hormone (GH) to promote cellular growth, differentiation, and repair
-
Stimulates muscle, cartilage, and connective tissue regeneration
-
Enhances tissue remodeling, cellular repair, and recovery
-
When stacked with Ipamorelin, can amplify GH-mediated effects
-
Research shows NAD+ co-administration may increase energy and exercise performance
Dosage Guidelines (Research Use)
-
Typical Dose: 50–100 mcg administered in the morning, fasted, before workouts
-
Cycle Length: 10–20 consecutive days, followed by an off-cycle of 4–8 weeks
-
Carbohydrates and fats may blunt GH-related effects; best administered 30 minutes before meals or 2 hours after eating
Side Effects (Research Use)
-
Increased hunger (can be beneficial depending on protocol)
-
Water retention
-
Tingling in extremities
-
Gradual dose escalation is recommended to minimize side effects
Useful Information
-
Class: Recombinant Insulin-like Growth Factor-1 analogue
-
Category: Growth Hormone Peptides
-
Primary Research Focus: Cellular growth, tissue repair, regeneration, and recovery






Reviews
There are no reviews yet.