Semax

Semax is a synthetic nootropic and neuroprotective heptapeptide, derived from an ACTH fragment. It is studied for cognitive enhancement, memory support, anxiety relief, and neuroprotection in research settings.

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For laboratory research use only. Not for human or animal use or consumption. Not a drug, food, dietary supplement, or cosmetic. Not approved by the FDA for any medical use.

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Description

Semax is a synthetic analogue of the adrenocorticotropic hormone (ACTH 4-10) fragment, designed for research into cognitive and neuroprotective effects. It is primarily studied for its ability to enhance memory, learning, focus, and resilience to neural stress.

Mechanism of Action

  • Modulates Brain-Derived Neurotrophic Factor (BDNF) and Nerve Growth Factor (NGF) pathways

  • Supports dopamine and serotonin balance to improve mood and focus

  • Reduces oxidative and ischemic stress in neural tissues

  • Promotes neuroplasticity and neuronal survival without affecting cortisol production

  • Intranasal administration allows rapid transport across the blood-brain barrier (~30 minutes onset)

Dosage Guidelines (Research Use)

  • Cognitive Enhancement: 500 mcg–1 mg per day, often divided into two doses

  • Treatment of Ischemic Stroke (research models): 1 mg four times daily for up to 10 days

  • Administration: Typically intranasal to ensure central nervous system bioavailability

  • Cycle Length: Tailored to study protocol; assess tolerance before increasing dosage

Important Notes

  • Designed for research purposes only; not for human or animal consumption

  • Dosage frequency and size should be adjusted per experimental requirements

  • Effects can vary depending on the subject and protocol

Useful Information

  • Class: Synthetic neuropeptide / cognitive & neuroprotective modulator

  • Primary Research Focus: Cognitive enhancement, memory consolidation, neuroprotection, anxiety relief

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