MOTS-c is a mitochondrial-derived regulatory peptide that supports metabolic health by enhancing glucose metabolism, fatty acid oxidation, and mitochondrial function. Commonly studied for longevity, metabolic regulation, and cellular stress adaptation.
$79.00
For laboratory research use only. Not for human or animal use or consumption. Not a drug, food, dietary supplement, or cosmetic. Not approved by the FDA for any medical use.
MOTS-c (Met-Arg-Trp-Glu-Met-Ile-Gln-Lys-Val-Gly-Gln-Tyr-Gln-Leu-Glu-Gln) is a 16-amino acid peptide encoded by the mitochondrial genome. Unlike nuclear-encoded peptides, MOTS-c directly influences cellular energy regulation and stress adaptation, playing a critical role in metabolic health and longevity research.
Activates AMP-activated protein kinase (AMPK) and PGC-1α pathways
Promotes fatty acid oxidation and improves glucose utilization
Enhances mitochondrial biogenesis and cellular energy efficiency
Supports resistance to metabolic and oxidative stress, making it valuable for longevity studies
General Dose: 5–10 mg per injection
Frequency: 2–3 times per week
Cycle Length: Commonly 4 weeks, followed by a break period
Important Note: Emerging data suggest MOTS-c may have limited stability (~10 minutes) post-reconstitution, warranting careful handling during experiments
Class: Mitochondrial-encoded regulatory peptide
Category: Metabolic Regulating Peptides
Primary Research Focus: Metabolic regulation, glucose homeostasis, mitochondrial function, and longevity
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