Melanotan I is a synthetic α-MSH analogue that stimulates melanocortin-1 receptors to increase melanin production, providing a natural-looking tan and photoprotective benefits. Commonly studied in research for UV protection, skin pigmentation, and antioxidant effects.
$49.00
For laboratory research use only. Not for human or animal use or consumption. Not a drug, food, dietary supplement, or cosmetic. Not approved by the FDA for any medical use.
Melanotan I (Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH₂) is a synthetic analogue of alpha-melanocyte-stimulating hormone (α-MSH) designed to activate melanocortin-1 receptors (MC1R) on melanocytes. This activation enhances melanin synthesis, resulting in a gradual, natural-appearing tan while also offering photoprotective and antioxidant benefits.
Selectively binds MC1R on melanocytes to stimulate melanogenesis
Provides photoprotection and antioxidant support to skin cells
Reduces erythema and protects DNA from UV-induced damage
Exhibits anti-inflammatory effects, supporting skin recovery after UV exposure
Unlike Melanotan II, it has minimal effect on MC3R/MC4R, so it does not significantly influence libido or appetite
Initial Loading Phase: 1 mg per day for 10 consecutive days
Maintenance Phase: 2 mg per week, divided into one or two injections
Administration Notes: More effective when paired with UV exposure (sunlight or tanning beds)
Mild side effects may include temporary stomach cramping for 15–30 minutes post-injection
Class: Synthetic α-MSH analogue / melanocortin receptor agonist
Category: Cosmetic & Skin Support Peptides
Primary Research Focus: Melanin production, photoprotection, antioxidant activity
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