Description
KPV (Lys-Pro-Val) is a naturally occurring tripeptide derived from the C-terminal region of alpha-melanocyte-stimulating hormone (α-MSH). It is studied for its anti-inflammatory, cytoprotective, and immune-modulating effects.
Mechanism of Action
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Activates melanocortin-1 and melanocortin-3 receptors (MC1R / MC3R)
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Suppresses key inflammatory pathways, including NF-κB, TNF-α, IL-1β, and IL-6
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Restores immune balance at the cellular level
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Exhibits cytoprotective and antimicrobial effects, beneficial for skin, gut, and systemic inflammatory conditions
Dosage Guidelines (Research Use)
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Typical Dose: 200–500 µg per day
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Administration: Subcutaneous injection for research purposes
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Cycle Length: Continue until the desired experimental outcome is achieved
Important Notes
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Discontinue use if skin irritation occurs or worsens
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Designed for laboratory research use only
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Not intended for human or animal consumption or medical use
Useful Information
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Class: Anti-inflammatory α-MSH tripeptide fragment
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Category: Repair Peptides
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Primary Research Focus: Anti-inflammatory signaling, immune modulation, skin and tissue repair






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